Molecular devices based on DNA

DNA-based molecular templates and devices

vii

Nanomechanical devices based on DNA.

Biomolecular compounds, such as proteins and nucleic acids, which are evolutionary optimized, with respect to specificity of binding to their target structure as well as to functionality, for distinct biochemical transformation and translocation, are currently explored as building blocks in the ™bottom-up∫ self-assembly of nanometer-scale functional devices. [1] So far, applications include the...

Molecular Electronic Devices based on Carotenoid Derivatives

The production of devices in nanoscale with specific molecular rectifying function is one of the most significant goals in state-of-art technology. In this work we show by ab initio quantum mechanics calculations coupled with non-equilibrium Green function, the design of an organic two-terminal device. These molecular structures have molecular source and drain with several bridge length (from f...

Design of molecular logic devices based on a programmable DNA-regulated semisynthetic enzyme.

High-Fidelity DNA Hybridization Using Programmable Molecular DNA Devices

The hybridization of complementary nucleic acid strands is the most basic of all reactions involving nucleic acids, but has a major limitation: the specificity of hybridization reactions depends critically on the lengths of the complementary pairs of strands and can drop (in the presence of other competing strands whose sequences are close to that of a given target strand) to very low values if...